HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: PHF10 (Q8WUB8)
PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a) (XAP135)
Gene: PHF10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 801 Hs			1 498
+	Mm
		101544 F8VQD1_MOUSE (290-799): 7.7e-34: 142: 13.93		PHF10_MOUSE (3-498): 0: 534: 95.97
+	Hs
		631426 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		CHD4_HUMAN (279-493): 4.97e-38: 150: 17.05
+	Hs
		631414 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		CHD3_HUMAN (273-493): 5.18e-37: 147: 17.73
+	Hs
		631557 BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00		RSF1_HUMAN (173-493): 1.09e-33: 137: 18.02
+	Hs
		1059625 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		CHD4_HUMAN (279-493): 4.97e-38: 150: 17.05
+	Hs
		1067079 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		REQU_HUMAN (255-478): 6.43e-38: 144: 28.57
+	Hs
		1067107 BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56		RSF1_HUMAN (173-493): 1.09e-33: 137: 18.02
+	Hs
		244447 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		CHD4_HUMAN (279-493): 4.97e-38: 150: 17.05
+	Hs
		244356 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		CHD3_HUMAN (273-493): 5.18e-37: 147: 17.73
+	Hs
		244728 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		REQU_HUMAN (255-478): 6.43e-38: 144: 28.57
+	Hs
		244060 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		KDM5C_HUMAN (173-489): 3.2e-35: 142: 17.83
+	Hs
		244826 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		RSF1_HUMAN (173-493): 1.09e-33: 137: 18.02
+	Hs
		244762 BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89		PF21A_HUMAN (232-482): 2.05e-33: 136: 17.31
+	Mm
		70929 EP300_MOUSE (202-448): 1.26e-40: 164: 24.71		CHD4_MOUSE (279-493): 9.42e-38: 150: 17.05
+	Hs
		998717 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		CHD4_HUMAN (279-493): 4.97e-38: 150: 17.05
+	Hs
		998938 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		DPF3_HUMAN (274-478): 2.11e-39: 148: 29.67
+	Hs
		998619 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		CHD3_HUMAN (273-493): 5.18e-37: 147: 17.73
+	Hs
		998941 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		KAT6A_HUMAN (366-497): 1.52e-34: 140: 40.74
+	Hs
		999001 EP300_HUMAN (31-183): 5.52e-39: 159: 30.72		RSF1_HUMAN (173-493): 1.09e-33: 137: 18.02
+	Hs
		319179 BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79		CHD3_HUMAN (273-493): 5.18e-37: 147: 17.73