HitPredict

Interactor 1: RS2 (P25443)
Small ribosomal subunit protein uS5 (40S ribosomal protein S2) (Omnipotent suppressor protein SUP44) (RP12) (S4) (YS5)
Gene: RPS2

Interactor 2: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31062022, 21825077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 254 Sc			1 606
+	Hs
		550987 RS2_HUMAN (29-253): 1.32e-120: 347: 59.29		DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61
+	Sc
		632065 RS2_YEAST (1-254): 1.18e-109: 318: 100.00		HAS1_YEAST (6-467): 1.01e-156: 460: 30.98
+	Sc
		415897 RS2_YEAST (1-254): 1.18e-109: 318: 100.00		DED1_YEAST (3-402): 8.68e-139: 418: 25.55
+	Sc
		624027 RS2_YEAST (1-254): 1.18e-109: 318: 100.00		DBP2_YEAST (2-402): 7.47e-126: 383: 25.43
+	Sc
		624208 RS2_YEAST (1-254): 1.18e-109: 318: 100.00		DBP1_YEAST (2-406): 1.57e-119: 369: 24.76
+	Sc
		415936 RT05_YEAST (70-225): 1.07e-44: 154: 24.20		DED1_YEAST (3-402): 8.68e-139: 418: 25.55
+	Hs
		550750 RS2_HUMAN (29-253): 1.32e-120: 347: 59.29		DDX10_HUMAN (21-472): 5.23e-47: 179: 29.67
+	Sc
		593589 RS2_YEAST (1-254): 1.18e-109: 318: 100.00		DBP4_YEAST (21-467): 7e-51: 189: 31.36
+	Sc
		631854 RS2_YEAST (1-254): 1.18e-109: 318: 100.00		RRP3_YEAST (12-425): 1.31e-50: 184: 31.97
+	Sc
		631766 RS2_YEAST (1-254): 1.18e-109: 318: 100.00		DRS1_YEAST (21-392): 3.9e-47: 178: 31.75
+	Ec
		462300 RS5_ECOLI (69-223): 3.3e-45: 151: 28.39		DEAD_ECOLI (18-393): 1.01e-48: 181: 32.99