HitPredict

Interactor 1: PSB3 (P25451)
Proteasome subunit beta type-3 (Macropain subunit PUP3) (Multicatalytic endopeptidase complex subunit PUP3) (Proteasome component PUP3)
Gene: PUP3

Interactor 2: PSB1 (P38624)
Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit PRE3) (Multicatalytic endopeptidase complex subunit PRE3) (Proteasome component PRE3) (Proteinase YSCE subunit PRE3)
Gene: PRE3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 9087403, 16429126, 37968396
Identification Methods x-ray crystallography, affinity chromatography technology, tandem affinity purification
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019774 - proteasome core complex, beta-subunit complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 205
Sc

1 215
+ Dm
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+ Sp
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+ Dm
+ Sc
+ Dm
+ Dm
+ Dm
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+ Hs
+ Sc
+ Sc
+ Sc
+ Hs
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+ Hs

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Last updated: 15 Jul 2024