HitPredict

Interactor 1: TYY1 (P25490)
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
Gene: YY1

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37059091
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 1834
+	Hs
		177626 TYY2_HUMAN (1-411): 9.11e-102: 308: 54.26		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1222623 ZN629_HUMAN (138-320): 3.83e-13: 73.2: 8.48		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		632636 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		632731 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		632785 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		SRCAP_HUMAN (1206-1787): 5.26e-09: 64: 11.45
+	Hs
		632836 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		632968 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		CABIN_HUMAN (880-1364): 9.59e-09: 63.1: 13.91
+	Hs
		1056958 ZN251_HUMAN (29-295): 6.31e-40: 152: 8.41		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		1060167 MTF1_HUMAN (351-411): 2.81e-09: 61.2: 45.90		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57