HitPredict

Interactor 1: TYY1 (P25490)
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
Gene: YY1

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000976 - transcription cis-regulatory region binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0016363 - nuclear matrix
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 651
+	Hs
		319123 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		632707 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		632836 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Mm
		70911 TYY1_MOUSE (1-414): 7.48e-133: 389: 94.23		EP300_MOUSE (42-238): 3.03e-40: 160: 22.93
+	Hs
		600082 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		TAF1_HUMAN (58-534): 1.25e-34: 143: 13.99
+	Hs
		631346 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		632897 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23
+	Hs
		632711 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		BPTF_HUMAN (133-233): 1.15e-18: 93: 29.52
+	Hs
		1354548 ZN629_HUMAN (138-320): 3.83e-13: 73.2: 8.48		BRPF3_HUMAN (3-537): 1.76e-54: 203: 16.33
+	Hs
		319360 ZN629_HUMAN (138-320): 3.83e-13: 73.2: 8.48		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		735048 ZNF76_HUMAN (347-411): 2.64e-11: 67.4: 44.62		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		998719 MTF1_HUMAN (351-411): 2.81e-09: 61.2: 45.90		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1060167 MTF1_HUMAN (351-411): 2.81e-09: 61.2: 45.90		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		600194 FEZF2_HUMAN (299-404): 1.47e-13: 73.9: 36.70		TAF1_HUMAN (58-534): 1.25e-34: 143: 13.99