HitPredict

Interactor 1: TYY1 (P25490)
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
Gene: YY1

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 601
+	Hs
		297459 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		TOX4_HUMAN (339-528): 4.7e-37: 148: 24.76
+	Hs
		632796 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		632642 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Mm
		818696 TYY1_MOUSE (1-414): 7.48e-133: 389: 94.23		SOX2_MOUSE (375-551): 5.31e-32: 128: 16.38
+	Hs
		449547 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		617245 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		SP100_HUMAN (388-490): 1.64e-16: 85.3: 30.48
+	Hs
		632868 TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		818499 ZNF71_HUMAN (36-348): 2.24e-86: 273: 15.95		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Hs
		1219761 ZSC29_HUMAN (250-381): 1.06e-39: 153: 31.58		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		818150 ZN787_HUMAN (303-411): 4.94e-21: 95.9: 47.27		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Hs
		563474 ZNF22_HUMAN (303-382): 2.37e-12: 67.8: 41.98		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		1300976 ZN629_HUMAN (138-320): 3.83e-13: 73.2: 8.48		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		1078419 ZKSC8_HUMAN (3-184): 7.13e-13: 72: 9.42		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29