HitPredict

Interactor 1: MRC1 (P25588)
Mediator of replication checkpoint protein 1 (DNA replication checkpoint mediator MRC1)
Gene: MRC1

Interactor 2: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25870112, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0031298 - replication fork protection complex GO:0031509 - subtelomeric heterochromatin formation GO:0043596 - nuclear replication fork
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1096 Sc			1 775
+	Sc
		634863 MRC1_YEAST (1-1096): 0: 2005: 100.00		MCM4_YEAST (19-747): 0: 659: 28.05
+	Sc
		634888 MRC1_YEAST (1-1096): 0: 2005: 100.00		MCM6_YEAST (17-717): 0: 625: 26.09
+	Sc
		634861 MRC1_YEAST (1-1096): 0: 2005: 100.00		MCM2_YEAST (27-691): 7.37e-92: 308: 31.78