Interactor 1: STP22 (P25604)
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease (ESCRT-I complex subunit VPS23) (Vacuolar protein sorting-associated protein 23)
Gene: STP22

Interactor 2: VPS27 (P40343)
Vacuolar protein sorting-associated protein 27 (Golgi retention defective protein 11)
Gene: VPS27

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 12900393, 14581452, 21505419, 15086794, 37968396, 17513562, 22918958
Identification Methods affinity chromatography technology, pull down, two hybrid, x-ray crystallography, protein complementation assay, isothermal titration calorimetry
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0006623 - protein targeting to vacuole
GO:0043130 - ubiquitin binding
GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045324 - late endosome to vacuole transport
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 385
Sc

1 622
+ Hs
+ Mm
+ At
+ Hs
+ Hs
+ Ce
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024