HitPredict

Interactor 1: BUD23 (P25627)
18S rRNA (guanine(1575)-N(7))-methyltransferase (EC 2.1.1.309) (Bud site selection protein 23)
Gene: BUD23

Interactor 2: TR112 (P53738)
Multifunctional methyltransferase subunit TRM112 (eRF1 methyltransferase subunit TRM112) (eRF1 MTase subunit TRM112) (tRNA methyltransferase 112)
Gene: TRM112

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 22956767, 24710271, 25489090, 22493060, 37968396
Identification Methods two hybrid, x-ray crystallography, pull down, affinity chromatography technology, molecular sieving
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Methyltransf_11~Trm112p
Common GO terms GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0043527 - tRNA methyltransferase complex
GO:0070476 - rRNA (guanine-N7)-methylation
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 275
Sc

1 135
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024