HitPredict

Interactor 1: PWP2 (P25635)
Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)
Gene: PWP2

Interactor 2: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26673895, 25474739
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 923 Sc			1 1084
+	Hs
		162766 PWP2_HUMAN (1-897): 1.24e-171: 524: 40.41		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Xl
		1155635 Q6PCE6_XENLA (1-434): 6.51e-74: 261: 15.19		Q6NS03_XENLA (3-1084): 0: 852: 46.77
+	Xl
		1150304 Q6DJD1_XENLA (4-480): 4.06e-48: 188: 12.45		Q6NS03_XENLA (3-1084): 0: 852: 46.77
+	Hs
		162576 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Xl
		1150112 Q6DCY8_XENLA (554-909): 2.3e-37: 145: 7.84		Q6NS03_XENLA (3-1084): 0: 852: 46.77
+	Hs
		162536 COPA_HUMAN (2-394): 3.56e-29: 128: 9.05		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Hs
		163237 TBL1R_HUMAN (19-222): 1.04e-26: 117: 17.21		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Xl
		1155663 TB1RA_XENLA (19-222): 3.01e-26: 115: 16.74		Q6NS03_XENLA (3-1084): 0: 852: 46.77
+	Xl
		1119810 Q52L18_XENLA (1-90): 9.15e-18: 90.7: 14.29		Q6NS03_XENLA (3-1084): 0: 852: 46.77
+	Hs
		163123 SNR40_HUMAN (143-502): 1.03e-16: 84.7: 22.28		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Hs
		162602 GBB2_HUMAN (342-550): 1.77e-09: 62.4: 21.46		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Mm
		903678 WDR5_MOUSE (546-909): 5.2e-38: 147: 7.95		XPO7_MOUSE (11-1030): 1.87e-146: 468: 13.68