HitPredict

Interactor 1: PAT1 (P25644)
Deadenylation-dependent mRNA-decapping factor PAT1 (DNA topoisomerase 2-associated protein PAT1) (Decapping activator and translational repressor PAT1) (Topoisomerase II-associated protein PAT1) (mRNA turnover protein 1)
Gene: PAT1

Interactor 2: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.654

Property	Details
Experiments	11283351, 11027275, 26673895
Identification Methods	two hybrid pooling approach, two hybrid, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 796 Sc			1 1084
+	Sp
		194954 PAT1_SCHPO (1-788): 1.49e-177: 530: 24.83		XPO1_SCHPO (1-1083): 0: 817: 55.31
+	Xl
		1118785 PATL2_XENLA (107-685): 3.17e-112: 359: 16.17		Q6NS03_XENLA (3-1084): 0: 852: 46.77
+	Hs
		162934 PATL1_HUMAN (51-684): 1.74e-79: 273: 16.99		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Hs
		162281 SC24D_HUMAN (66-265): 3.21e-09: 62.8: 13.73		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Hs
		162539 SC24C_HUMAN (57-239): 9.39e-09: 61.3: 17.86		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Xl
		1145048 Q641I5_XENLA (52-233): 7.09e-09: 61.7: 14.52		Q6NS03_XENLA (3-1084): 0: 852: 46.77