Interactor 1: CDC50 (P25656)
Phospholipid-transporting ATPase accessory subunit CDC50 (Cell division control protein 50)
Gene: CDC50

Interactor 2: ATC3 (P39524)
Phospholipid-transporting ATPase DRS2 (EC 7.6.2.1)
Gene: DRS2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 28302728, 19411703, 15090616, 24019533, 16956384, 25393116, 31243363, 31515475, 19968326, 37968396, 22791719
Identification Methods pull down, affinity chromatography technology, biochemical, x-ray crystallography, two hybrid, protein complementation assay, ubiquitin reconstruction, anti tag coimmunoprecipitation, 3D electron microscopy, molecular sieving
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC50~PhoLip_ATPase_C, CDC50~PhoLip_ATPase_N
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005802 - trans-Golgi network
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0045332 - phospholipid translocation
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 391
Sc

1 1355
+ Sc
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024