Interactor 1: DNJB1 (P25685)
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)
Gene: DNAJB1

Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.701

The method score is based on:

Property Details
Experiments 35271311, 16611982, 21163940, 25036637
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0051082 - unfolded protein binding
GO:0051087 - protein-folding chaperone binding
GO:0070062 - extracellular exosome
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 340
Hs

1 378
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024