HitPredict

Interactor 1: DNJB2 (P25686)
DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1)
Gene: DNAJB2

Interactor 2: MLF1 (P58340)
Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1)
Gene: MLF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 324 Hs			1 268
+	Hs
		257968 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		MLF1_HUMAN (1-268): 9.35e-137: 388: 100.00
+	Hs
		636488 DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00		MLF2_HUMAN (1-233): 2.16e-88: 264: 37.55
+	Hs
		885582 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		MLF1_HUMAN (1-268): 9.35e-137: 388: 100.00
+	Hs
		885622 DNJB4_HUMAN (2-238): 5.01e-44: 155: 28.98		MLF1_HUMAN (1-268): 9.35e-137: 388: 100.00
+	Hs
		636295 DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63		MLF1_HUMAN (1-268): 9.35e-137: 388: 100.00
+	Hs
		258040 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		MLF2_HUMAN (1-233): 2.16e-88: 264: 37.55
+	Hs
		1078368 DNJB4_HUMAN (2-238): 5.01e-44: 155: 28.98		MLF2_HUMAN (1-233): 2.16e-88: 264: 37.55
+	Hs
		279300 DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88		MLF2_HUMAN (1-233): 2.16e-88: 264: 37.55
+	Hs
		636339 DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63		MLF2_HUMAN (1-233): 2.16e-88: 264: 37.55
+	Dm
		1096103 DNAJ1_DROME (2-242): 1.7e-45: 159: 28.86		MLF_DROME (80-231): 6.76e-58: 190: 37.42