HitPredict

Interactor 1: DNJB2 (P25686)
DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1)
Gene: DNAJB2

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 324 Hs			1 412
+	Hs
		258022 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		1053087 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		1053045 DNJB7_HUMAN (1-223): 6.35e-62: 201: 40.56		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		279297 DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		636333 DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		636460 DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		257927 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		258010 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		118655 DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		118767 DNJB3_HUMAN (1-131): 1.76e-44: 150: 53.44		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		684896 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		1034936 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		1034884 DJC21_HUMAN (1-317): 2.08e-62: 208: 20.94		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		279279 DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		685080 DNJB4_HUMAN (2-238): 5.01e-44: 155: 28.98		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		636254 DNJB1_HUMAN (2-161): 3.26e-43: 153: 40.63		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		279295 DNJB5_HUMAN (2-239): 5.52e-44: 155: 25.88		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		684903 DJB14_HUMAN (2-150): 3.25e-40: 146: 34.67		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		887185 DJB13_HUMAN (3-136): 5.03e-42: 149: 41.73		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21