HitPredict

Interactor 1: DNJB2 (P25686)
DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1)
Gene: DNAJB2

Interactor 2: Q53FC7 (Q53FC7)
Heat shock 70kDa protein 6 (HSP70B') variant
Gene: Q53FC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 324 Hs			1 643
+	Hs
		564009 DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00		HSP76_HUMAN (1-643): 0: 990: 99.22
+	Hs
		636461 DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00		HS71L_HUMAN (1-643): 0: 981: 78.85
+	Hs
		503464 DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Hs
		483774 DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00		HS71B_HUMAN (5-643): 0: 954: 81.85
+	Hs
		636469 DNJB2_HUMAN (1-324): 1.9e-125: 363: 100.00		HSP72_HUMAN (3-643): 0: 945: 77.14
+	Hs
		257907 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		HSP76_HUMAN (1-643): 0: 990: 99.22
+	Hs
		257928 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		HS71L_HUMAN (1-643): 0: 981: 78.85
+	Hs
		257901 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Hs
		257895 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		HS71A_HUMAN (5-643): 0: 954: 81.85
+	Hs
		564130 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		HSP76_HUMAN (1-643): 0: 990: 99.22
+	Hs
		257961 DNJB6_HUMAN (1-283): 7.47e-82: 252: 47.63		HSP72_HUMAN (3-643): 0: 945: 77.14
+	Mm
		222719 DNJB6_MOUSE (1-273): 4.6e-75: 236: 41.28		HS71B_MOUSE (5-643): 0: 960: 80.31
+	Hs
		564108 DNJB7_HUMAN (1-223): 6.35e-62: 201: 40.56		HSP76_HUMAN (1-643): 0: 990: 99.22
+	Hs
		714022 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		HS71L_HUMAN (1-643): 0: 981: 78.85
+	Hs
		504431 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Hs
		564202 DJB11_HUMAN (2-228): 1.38e-51: 175: 27.31		HSP76_HUMAN (1-643): 0: 990: 99.22
+	Hs
		714087 DJB11_HUMAN (2-228): 1.38e-51: 175: 27.31		HS71L_HUMAN (1-643): 0: 981: 78.85
+	Hs
		871683 DNJB8_HUMAN (1-208): 1.52e-66: 210: 47.79		HSP72_HUMAN (3-643): 0: 945: 77.14
+	Hs
		504897 DJB11_HUMAN (2-228): 1.38e-51: 175: 27.31		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Ce
		450534 Q20774_CAEEL (2-263): 8.25e-50: 170: 26.57		HSP1_CAEEL (4-643): 0: 944: 76.44