Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48
Interactor 2: NPL4 (P33755)
Nuclear protein localization protein 4 (HMG-CoA reductase degradation protein 4)
Gene: NPL4
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11283351, 11805826, 15200949, 16554755, 16429126, 16179952, 29950310, 37311459, 21211725, 22940862, 16427015, 11733065, 11598205, 16619026, 37968396, 16179953, 17289586 |
| Identification Methods | two hybrid pooling approach, tandem affinity purification, affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~NPL4, AAA~zf-NPL4 |
| Common GO terms | GO:0000837 - Doa10p ubiquitin ligase complex GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex GO:0005634 - nucleus GO:0006274 - DNA replication termination GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins and 15 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
