Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Interactor 2: VMS1 (Q04311)
tRNA endonuclease VMS1 (EC 3.1.-.-) (VCP/CDC48-associated mitochondrial stress-responsive protein 1)
Gene: VMS1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 11805826, 21070972, 23468520, 16554755, 16429126, 31189955, 21148305, 21896481, 22718752, 37968396, 24351022
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
GO:0036266 - Cdc48p-Npl4p-Vms1p AAA ATPase complex
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 835
Sc

1 632
+ Sp
+ Ce
+ Mm
+ Hs

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Last updated: 15 Jul 2024