Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Interactor 2: HRD3 (Q05787)
ERAD-associated E3 ubiquitin-protein ligase component HRD3 (HMG-CoA reductase degradation protein 3)
Gene: HRD3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.709

The method score is based on:

Property Details
Experiments 37968396, 16619026, 20005842, 19696741, 16873066
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005789 - endoplasmic reticulum membrane
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 835
Sc

1 833
+ Hs
+ Hs

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Last updated: 15 Jul 2024