HitPredict

Interactor 1: ATPA (P25705)
ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha)
Gene: ATP5F1A

Interactor 2: ATPO (P48047)
ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP)
Gene: ATP5PO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

The method score is based on:

Property	Details
Experiments	27499296, 30021884, 35235311, 34349018, 37071682
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ATP-synt_ab_N~OSCP
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0005753 - mitochondrial proton-transporting ATP synthase complex GO:0005886 - plasma membrane GO:0006754 - ATP biosynthetic process and 4 others more... GO:0015986 - proton motive force-driven ATP synthesis GO:0042776 - proton motive force-driven mitochondrial ATP synthesis GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	553
Hs

1	213

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024