HitPredict

Interactor 1: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Interactor 2: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.944

The method score is based on:

Property Details
Experiments 28292943, 29568061, 34689164, 36949045, 14733938, unassigned1655
Identification Methods pull down, affinity chromatography technology, proximity labelling technology, two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0001530 - lipopolysaccharide binding
GO:0002376 - immune system process
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus
GO:0005634 - nucleus
and 8 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 263
Hs

1 263
+ Zm
+ Ss
+ Hs
+ Hs
+ Hs
+ Ss
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024