HitPredict

Interactor 1: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Interactor 2: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	25416956, 19060904, unassigned1654
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 574
+	Hs
		656159 PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81		TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00
+	Hs
		637595 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51
+	Hs
		574598 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		ARF4_HUMAN (393-568): 1.47e-70: 226: 55.11
+	Hs
		637550 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		RAB1B_HUMAN (397-569): 7.05e-60: 199: 15.17