HitPredict

Interactor 1: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17353931, 14743216
Identification Methods	anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 522
+	Hs
		893778 PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		638223 PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		129531 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		TRAF5_HUMAN (43-500): 4.95e-87: 280: 25.23
+	Hs
		637402 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		536731 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		637398 PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Dm
		1368927 Q9VK14_DROME (1-263): 3.32e-100: 295: 49.81		Q9VJW5_DROME (55-177): 1.51e-17: 85.7: 32.58