HitPredict

Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: PSA4 (P25789)
Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L)
Gene: PSMA4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 28292943, 31114588, 33961781, 35271311, 37071682, 12376572, 15225636, 14733938, 19193609, 17948026, 15887188, 9311996
Identification Methods pull down, affinity chromatography technology, cross-linking study, two hybrid, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 234
Hs

1 261
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024