HitPredict

Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: PSB10 (P40306)
Proteasome subunit beta type-10 (EC 3.4.25.1) (Low molecular mass protein 10) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1) (Proteasome MECl-1) (Proteasome subunit beta-2i)
Gene: PSMB10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 33961781, 20937868, 19193609, 17948026, 15887188
Identification Methods affinity chromatography technology, two hybrid, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pr_beta_C~Proteasome, Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005839 - proteasome core complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 234
Hs

1 273
+ Hs
+ At
+ Sp
+ At
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sp
+ Hs
+ Hs
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ph

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024