HitPredict

Interactor 1: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3)
Gene: PSMA2

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	27497298, 27503909, 33961781
Identification Methods	two hybrid, affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 234 Hs			1 522
+	Hs
		656346 PSA5_HUMAN (1-233): 2.69e-97: 285: 30.96		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		893775 PSA6_HUMAN (2-234): 2.68e-90: 267: 34.73		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		156380 PSA7_HUMAN (6-231): 1.49e-89: 266: 36.52		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		637614 PSA1_HUMAN (1-233): 1.31e-89: 266: 30.67		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		638222 PSA4_HUMAN (4-211): 1.24e-42: 146: 38.68		FBX7_HUMAN (1-522): 0: 1102: 100.00