HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: HEN1 (Q02575)
Helix-loop-helix protein 1 (HEN-1) (Class A basic helix-loop-helix protein 35) (bHLHa35) (Nescient helix loop helix 1) (NSCL-1)
Gene: NHLH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	12878195
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 133
+	Hs
		638295 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		TAL2_HUMAN (74-131): 8.34e-26: 95.2: 56.90
+	Hs
		210862 LMO4_HUMAN (11-147): 3.1e-39: 132: 42.34		TCF21_HUMAN (2-131): 3.64e-26: 98.3: 29.32
+	Hs
		638508 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		TAL2_HUMAN (74-131): 8.34e-26: 95.2: 56.90
+	Mm
		603898 RBTN2_MOUSE (1-158): 3.35e-41: 137: 99.37		TAL1_MOUSE (76-132): 6.09e-20: 84.9: 59.65
+	Hs
		568179 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		TAL1_HUMAN (76-132): 3.36e-20: 85.7: 59.65
+	Hs
		524537 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		LYL1_HUMAN (36-131): 1.13e-19: 83.8: 42.71
+	Mm
		1143746 LMO3_MOUSE (30-156): 5.7e-39: 130: 58.27		TAL2_MOUSE (81-131): 1.54e-23: 89.6: 64.71
+	Mm
		1143747 RBTN1_MOUSE (11-150): 3.96e-38: 128: 52.86		TAL2_MOUSE (81-131): 1.54e-23: 89.6: 64.71
+	Mm
		604035 LMO3_MOUSE (30-156): 5.7e-39: 130: 58.27		TAL1_MOUSE (76-132): 6.09e-20: 84.9: 59.65
+	Hs
		568180 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		TAL1_HUMAN (76-132): 3.36e-20: 85.7: 59.65
+	Hs
		524538 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		LYL1_HUMAN (36-131): 1.13e-19: 83.8: 42.71
+	Dm
		114761 M9PD53_DROME (2-86): 7.78e-15: 72.3: 17.44		Q9VHG3_DROME (12-132): 2.51e-26: 100: 29.10
+	Dm
		1368265 Q9VJ00_DROME (2-86): 1.05e-14: 71.9: 17.44		Q9W4I4_DROME (54-132): 2.47e-26: 98.3: 84.81
+	Dm
		112565 M9NCY1_DROME (2-86): 7.53e-12: 63.8: 17.44		Q9W4I4_DROME (54-132): 2.47e-26: 98.3: 84.81
+	Dm
		1359764 Q9V472_DROME (94-155): 1.72e-09: 56.9: 22.58		Q9VHG3_DROME (12-132): 2.51e-26: 100: 29.10