HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 572
+	Hs
		1080752 PDLI5_HUMAN (2-154): 5.97e-34: 126: 23.23		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		638418 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80
+	Hs
		638292 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		TRIP6_HUMAN (63-571): 6e-66: 224: 32.82
+	Hs
		1251413 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61
+	Hs
		823405 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		823508 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80
+	Hs
		823403 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		TRIP6_HUMAN (63-571): 6e-66: 224: 32.82
+	Hs
		238981 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		LPXN_HUMAN (221-570): 4.84e-47: 170: 18.75
+	Hs
		238949 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		LPXN_HUMAN (221-570): 4.84e-47: 170: 18.75
+	Hs
		823454 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Hs
		638485 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Hs
		1293409 PDLI5_HUMAN (2-154): 5.97e-34: 126: 23.23		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		823353 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Ce
		107727 G5EFL5_CAEEL (2-83): 7.68e-18: 81.1: 19.28		PXL1_CAEEL (355-501): 2.4e-28: 119: 27.03
+	Hs
		638284 RBTN2_HUMAN (1-158): 4.5e-41: 136: 100.00		FHL3_HUMAN (410-544): 1.63e-09: 61.2: 28.99
+	Hs
		816263 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		LIMS1_HUMAN (383-566): 1.09e-10: 65.1: 25.95
+	Hs
		903714 LMO4_HUMAN (11-147): 3.1e-39: 132: 42.34		FHL3_HUMAN (410-544): 1.63e-09: 61.2: 28.99
+	Ce
		589701 LIN11_CAEEL (30-153): 1.14e-20: 88.6: 34.40		ZYX_CAEEL (444-571): 2.34e-17: 87.4: 24.62
+	Hs
		816231 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		LIMS1_HUMAN (383-566): 1.09e-10: 65.1: 25.95
+	Hs
		200167 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		TGFI1_HUMAN (377-441): 9.8e-10: 63: 32.31