HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	16189514
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 1210
+	Hs
		1296441 LHX6_HUMAN (7-153): 2.16e-38: 135: 27.70		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1296429 LHX3_HUMAN (92-155): 2.6e-12: 65: 23.44		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		839806 LHX2_HUMAN (94-152): 3.4e-11: 61.9: 25.42		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1281166 LHX4_HUMAN (89-155): 5.05e-11: 61.5: 26.87		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		822665 LHX1_HUMAN (93-155): 1.92e-10: 59.6: 19.05		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1334137 LHX3_HUMAN (92-155): 2.6e-12: 65: 23.44		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		839827 LHX2_HUMAN (94-152): 3.4e-11: 61.9: 25.42		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		1281184 LHX4_HUMAN (89-155): 5.05e-11: 61.5: 26.87		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		822681 LHX1_HUMAN (93-155): 1.92e-10: 59.6: 19.05		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		203710 LHX8_HUMAN (24-148): 1.1e-47: 159: 33.60		SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51
+	Hs
		1219793 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09
+	Hs
		823450 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		ANR52_HUMAN (394-767): 4.88e-48: 189: 12.40
+	Hs
		823441 PAXI_HUMAN (3-88): 1.08e-17: 80.8: 19.77		ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09
+	Hs
		1251433 LMO3_HUMAN (30-156): 5.7e-39: 130: 58.27		ASPP1_HUMAN (755-871): 8.39e-14: 78.5: 20.00
+	Hs
		638561 RBTN1_HUMAN (11-150): 2.04e-38: 129: 52.86		ASPP1_HUMAN (755-871): 8.39e-14: 78.5: 20.00
+	Hs
		257707 LHX9_HUMAN (94-152): 9.62e-11: 60.7: 27.12		ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86