HitPredict

Interactor 1: RBTN1 (P25800)
Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1)
Gene: LMO1

Interactor 2: SOX5 (P35711)
Transcription factor SOX-5
Gene: SOX5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	25416956, 21516116
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 763
+	Hs
		638236 RBTN2_HUMAN (7-149): 3.37e-46: 149: 54.17		SOX5_HUMAN (1-763): 0: 611: 100.00
+	Hs
		727819 LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78		SOX5_HUMAN (1-763): 0: 611: 100.00
+	Hs
		159893 RBTN1_HUMAN (1-156): 1.87e-43: 142: 100.00		HGS_HUMAN (99-513): 1.79e-48: 185: 14.02
+	Hs
		159943 LMO4_HUMAN (7-154): 3.11e-39: 132: 47.30		HGS_HUMAN (99-513): 1.79e-48: 185: 14.02
+	Hs
		818332 ISL2_HUMAN (21-142): 1.02e-48: 162: 39.84		SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10
+	Hs
		1148474 LHX8_HUMAN (14-143): 5.2e-48: 160: 40.00		PB1_HUMAN (458-668): 3.51e-31: 133: 12.68
+	Hs
		818493 LHX9_HUMAN (6-146): 8.11e-42: 145: 44.68		SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10
+	Ce
		590589 HM14_CAEEL (6-148): 3.71e-41: 142: 28.97		EGL13_CAEEL (525-673): 6.63e-33: 134: 55.48
+	Hs
		1293388 PDLI5_HUMAN (20-153): 2.33e-31: 119: 26.12		CIC_HUMAN (305-752): 1.22e-35: 147: 15.96
+	Hs
		1199163 LMO3_HUMAN (13-156): 1.16e-38: 130: 89.58		PB1_HUMAN (458-668): 3.51e-31: 133: 12.68
+	Hs
		638579 RBTN1_HUMAN (1-156): 1.87e-43: 142: 100.00		HM20A_HUMAN (457-654): 6.16e-29: 120: 11.94
+	Hs
		881817 LMO3_HUMAN (13-156): 1.16e-38: 130: 89.58		SOX10_HUMAN (450-698): 2.81e-31: 130: 22.89
+	Ce
		590592 HM14_CAEEL (6-148): 3.71e-41: 142: 28.97		SEM2_CAEEL (543-622): 9.16e-17: 85.1: 52.50
+	Hs
		1281169 LHX4_HUMAN (4-79): 1.31e-14: 71.5: 19.48		CIC_HUMAN (305-752): 1.22e-35: 147: 15.96
+	Hs
		1300973 LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78		CIC_HUMAN (305-752): 1.22e-35: 147: 15.96
+	Hs
		839810 LHX2_HUMAN (88-154): 3.56e-11: 61.9: 23.19		CIC_HUMAN (305-752): 1.22e-35: 147: 15.96
+	Hs
		1199179 LHX4_HUMAN (4-79): 1.31e-14: 71.5: 19.48		PB1_HUMAN (458-668): 3.51e-31: 133: 12.68
+	Hs
		1199211 LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78		PB1_HUMAN (458-668): 3.51e-31: 133: 12.68
+	Hs
		839772 LHX2_HUMAN (88-154): 3.56e-11: 61.9: 23.19		PB1_HUMAN (458-668): 3.51e-31: 133: 12.68
+	Dm
		1098042 Q9V472_DROME (4-88): 3.59e-15: 73.4: 23.26		DICH_DROME (474-706): 3.29e-27: 116: 23.93