HitPredict

Interactor 1: RBTN1 (P25800)
Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1)
Gene: LMO1

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 851
+	Hs
		638310 RBTN2_HUMAN (7-149): 3.37e-46: 149: 54.17		KANK2_HUMAN (1-851): 0: 559: 100.00
+	Hs
		903734 LMO4_HUMAN (7-154): 3.11e-39: 132: 47.30		KANK2_HUMAN (1-851): 0: 559: 100.00
+	Hs
		1144723 LMO3_HUMAN (13-156): 1.16e-38: 130: 89.58		KANK2_HUMAN (1-851): 0: 559: 100.00
+	Hs
		1144801 LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78		KANK2_HUMAN (1-851): 0: 559: 100.00
+	Hs
		823419 PAXI_HUMAN (85-152): 4.93e-13: 67.3: 24.64		KANK2_HUMAN (1-851): 0: 559: 100.00
+	Hs
		1144790 PDLI7_HUMAN (83-154): 2.06e-11: 62.6: 24.66		KANK2_HUMAN (1-851): 0: 559: 100.00
+	Hs
		903713 LMO4_HUMAN (7-154): 3.11e-39: 132: 47.30		ASPP2_HUMAN (48-840): 1.69e-69: 251: 15.57
+	Hs
		1281184 LHX4_HUMAN (4-79): 1.31e-14: 71.5: 19.48		EHMT1_HUMAN (43-849): 6.8e-84: 295: 14.00
+	Hs
		1334137 LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78		EHMT1_HUMAN (43-849): 6.8e-84: 295: 14.00
+	Hs
		1043721 LHX4_HUMAN (4-79): 1.31e-14: 71.5: 19.48		ASPP2_HUMAN (48-840): 1.69e-69: 251: 15.57
+	Hs
		257707 LHX9_HUMAN (6-146): 8.11e-42: 145: 44.68		ANR17_HUMAN (553-836): 3.23e-37: 154: 20.42
+	Hs
		1167334 LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78		BCOR_HUMAN (137-843): 3.57e-60: 225: 15.89
+	Hs
		839767 LHX2_HUMAN (88-154): 3.56e-11: 61.9: 23.19		BCOR_HUMAN (137-843): 3.57e-60: 225: 15.89
+	Hs
		823450 PAXI_HUMAN (85-152): 4.93e-13: 67.3: 24.64		ANR52_HUMAN (181-793): 1.55e-50: 194: 13.17
+	Hs
		638375 RBTN2_HUMAN (7-149): 3.37e-46: 149: 54.17		EHMT2_HUMAN (5-742): 2.01e-21: 102: 10.40
+	Hs
		1219793 LMO3_HUMAN (13-156): 1.16e-38: 130: 89.58		ANKH1_HUMAN (349-849): 1.99e-26: 119: 13.92
+	Hs
		823441 PAXI_HUMAN (85-152): 4.93e-13: 67.3: 24.64		ANKH1_HUMAN (349-849): 1.99e-26: 119: 13.92
+	Hs
		1281166 LHX4_HUMAN (4-79): 1.31e-14: 71.5: 19.48		EHMT2_HUMAN (5-742): 2.01e-21: 102: 10.40
+	Hs
		1296429 LHX3_HUMAN (4-79): 3.72e-14: 70.4: 20.78		EHMT2_HUMAN (5-742): 2.01e-21: 102: 10.40
+	Hs
		1344039 PDLI7_HUMAN (83-154): 2.06e-11: 62.6: 24.66		RAI14_HUMAN (710-831): 8.96e-21: 100: 27.05