HitPredict

Interactor 1: RGPD3 (A6NKT7)
RanBP2-like and GRIP domain-containing protein 3
Gene: RGPD3

Interactor 2: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1758 Hs			1 521
+	Hs
		134921 RGPD4_HUMAN (1-1758): 0: 2219: 98.29		IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00
+	Hs
		152769 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62
+	Hs
		853440 RGPD5_HUMAN (1-1758): 0: 2189: 95.56		IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62
+	Hs
		134964 RANB3_HUMAN (941-1512): 6.99e-37: 150: 14.02		IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00
+	Hs
		134854 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00
+	Hs
		131404 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	Hs
		134843 RANG_HUMAN (1309-1507): 3.28e-35: 135: 36.63		IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00
+	Sp
		293244 NU124_SCHPO (632-1325): 1.08e-49: 196: 15.30		IMA2_SCHPO (8-521): 3.88e-137: 409: 45.49
+	Hs
		131396 RANG_HUMAN (1309-1507): 3.28e-35: 135: 36.63		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	Hs
		131527 NUP50_HUMAN (1149-1467): 1.93e-32: 135: 18.01		IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80
+	At
		1280910 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		IMPA1_ARATH (1-521): 3.44e-158: 462: 43.72
+	At
		97810 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		IMPA2_ARATH (1-521): 1.4e-157: 461: 44.69
+	At
		285384 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		IMPA4_ARATH (1-521): 2.9e-155: 455: 41.64
+	At
		1320502 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		IMPA6_ARATH (1-521): 2.38e-153: 450: 43.41
+	At
		138100 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		IMPA3_ARATH (1-521): 7.35e-152: 446: 43.55
+	Hs
		834693 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62
+	Ce
		1091057 NUP50_CAEEL (1122-1465): 4.74e-38: 152: 14.69		IMA3_CAEEL (7-521): 4.37e-139: 412: 61.05
+	Sp
		293264 NUP61_SCHPO (1151-1471): 1.46e-37: 152: 19.63		IMA2_SCHPO (8-521): 3.88e-137: 409: 45.49
+	Hs
		834694 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		IMA5_HUMAN (3-521): 4.55e-135: 403: 45.46
+	At
		1320498 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		IMPA5_ARATH (1-521): 2.31e-138: 411: 39.96