HitPredict

Interactor 1: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Interactor 2: RL8B (P29453)
Large ribosomal subunit protein eL8B (60S ribosomal protein L8-B) (L4) (L4-1) (RP6) (YL5)
Gene: RPL8B

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 21825077
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000470 - maturation of LSU-rRNA GO:0003723 - RNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 606 Sc			1 256
+	Sc
		564361 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		RL8A_YEAST (1-256): 1.53e-106: 310: 97.27
+	Sc
		667268 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		RL8B_YEAST (1-256): 1.32e-106: 310: 100.00
+	Sc
		564228 DBP2_YEAST (2-402): 7.47e-126: 383: 25.43		RL8A_YEAST (1-256): 1.53e-106: 310: 97.27
+	Sc
		624041 DBP2_YEAST (2-402): 7.47e-126: 383: 25.43		RL8B_YEAST (1-256): 1.32e-106: 310: 100.00
+	Sc
		766347 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		SNU13_YEAST (101-219): 2.91e-34: 121: 19.33
+	Sc
		691415 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		NHP2_YEAST (107-230): 1.15e-30: 113: 23.39
+	Sc
		638680 SPB4_YEAST (1-606): 2.46e-149: 445: 100.00		NHP2_YEAST (107-230): 1.15e-30: 113: 23.39
+	Sc
		564223 DBP4_YEAST (21-467): 7e-51: 189: 31.36		RL8A_YEAST (1-256): 1.53e-106: 310: 97.27
+	Sc
		593601 DBP4_YEAST (21-467): 7e-51: 189: 31.36		RL8B_YEAST (1-256): 1.32e-106: 310: 100.00
+	Sc
		624047 DBP2_YEAST (2-402): 7.47e-126: 383: 25.43		NHP2_YEAST (107-230): 1.15e-30: 113: 23.39
+	Hs
		913506 DDX10_HUMAN (21-472): 5.23e-47: 179: 29.67		RL7A_HUMAN (11-253): 8e-109: 316: 56.79