HitPredict

Interactor 1: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Interactor 2: NUG1 (P40010)
Nuclear GTP-binding protein NUG1 (Nuclear GTPase 1)
Gene: NUG1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	36929751, 37968396, 16429126, 30568249, 37811893, 21825077
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 606 Sc			1 520
+	Sc
		766689 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		NUG1_YEAST (1-520): 2.9e-154: 452: 100.00
+	Hs
		1314090 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		GNL3_HUMAN (5-520): 5.39e-120: 365: 25.00
+	Hs
		1045708 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		NOG2_HUMAN (5-519): 4.99e-113: 353: 22.43
+	Sc
		864672 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		NOG2_YEAST (6-454): 1.32e-114: 349: 22.74
+	Dm
		1177944 DDX18_DROME (6-481): 1.03e-152: 457: 28.96		Q7JXU4_DROME (5-518): 1.45e-112: 350: 24.27
+	Dm
		1229284 DDX18_DROME (6-481): 1.03e-152: 457: 28.96		GNL3_DROME (2-518): 1.56e-111: 344: 30.89
+	Sc
		638825 SPB4_YEAST (1-606): 2.46e-149: 445: 100.00		NOG2_YEAST (6-454): 1.32e-114: 349: 22.74
+	Hs
		1045613 DDX46_HUMAN (2-597): 8.55e-134: 418: 21.15		NOG2_HUMAN (5-519): 4.99e-113: 353: 22.43
+	Sc
		859626 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		LSG1_YEAST (58-509): 1.02e-94: 302: 17.13
+	Hs
		1045635 DDX55_HUMAN (6-594): 5.25e-122: 375: 34.05		NOG2_HUMAN (5-519): 4.99e-113: 353: 22.43
+	Hs
		134190 DDX3X_HUMAN (4-406): 1.31e-116: 363: 24.40		GNL3_HUMAN (5-520): 5.39e-120: 365: 25.00
+	Sc
		624135 DBP2_YEAST (2-402): 7.47e-126: 383: 25.43		LSG1_YEAST (58-509): 1.02e-94: 302: 17.13
+	Sc
		699686 DRS1_YEAST (21-392): 3.9e-47: 178: 31.75		NUG1_YEAST (1-520): 2.9e-154: 452: 100.00
+	Sc
		638841 SPB4_YEAST (1-606): 2.46e-149: 445: 100.00		MTG1_YEAST (154-483): 5.47e-46: 166: 18.57
+	Dm
		1177948 DDX47_DROME (3-376): 3.85e-54: 194: 33.87		Q7JXU4_DROME (5-518): 1.45e-112: 350: 24.27
+	Dm
		1229288 DDX47_DROME (3-376): 3.85e-54: 194: 33.87		GNL3_DROME (2-518): 1.56e-111: 344: 30.89
+	Dm
		1177939 Y8611_DROME (23-437): 5.36e-47: 179: 29.23		Q7JXU4_DROME (5-518): 1.45e-112: 350: 24.27
+	Sc
		699707 DRS1_YEAST (21-392): 3.9e-47: 178: 31.75		NOG2_YEAST (6-454): 1.32e-114: 349: 22.74