HitPredict

Interactor 1: RGPD3 (A6NKT7)
RanBP2-like and GRIP domain-containing protein 3
Gene: RGPD3

Interactor 2: RANG (P43487)
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)
Gene: RANBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ran_BP1~Ran_BP1
Common GO terms	GO:0005096 - GTPase activator activity GO:0005643 - nuclear pore GO:0005737 - cytoplasm GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1758 Hs			1 201
+	Hs
		63872 RGPD3_HUMAN (1-1758): 0: 2226: 100.00		RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80
+	Hs
		152759 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80
+	Hs
		483407 RGPD5_HUMAN (1-1758): 0: 2189: 95.56		RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80
+	Hs
		483419 RGPD2_HUMAN (1-1756): 0: 2160: 95.05		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Hs
		483387 RGPD1_HUMAN (27-1756): 0: 2143: 95.32		RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83
+	Hs
		152813 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02
+	Hs
		796708 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Hs
		834692 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83
+	Ce
		1094054 Q21021_CAEEL (981-1468): 1.48e-29: 130: 19.96		Q21021_CAEEL (3-162): 3.51e-34: 129: 31.90
+	At
		1320510 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		NU50B_ARATH (32-184): 1.28e-30: 118: 22.08
+	Hs
		834867 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02