HitPredict

Interactor 1: RGPD3 (A6NKT7)
RanBP2-like and GRIP domain-containing protein 3
Gene: RGPD3

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rab_bind~Ras, Ran_BP1~Ras, Ras~TPR_8
Common GO terms	GO:0005643 - nuclear pore GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1758 Hs			1 216
+	Hs
		919141 RGPD4_HUMAN (1-1758): 0: 2219: 98.29		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		152774 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		919236 RGPD5_HUMAN (1-1758): 0: 2189: 95.56		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		483422 RGPD2_HUMAN (1-1756): 0: 2160: 95.05		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		483392 RGPD1_HUMAN (27-1756): 0: 2143: 95.32		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		914195 GCC2_HUMAN (1016-1758): 1.57e-56: 219: 23.48		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	At
		784991 NU50A_ARATH (775-1196): 7.38e-34: 139: 17.94		RAN1_ARATH (1-216): 1.39e-95: 279: 73.52
+	At
		784994 RBP1A_ARATH (1015-1240): 1.6e-35: 137: 26.32		RAN1_ARATH (1-216): 1.39e-95: 279: 73.52
+	Ce
		184992 Q21021_CAEEL (981-1468): 1.48e-29: 130: 19.96		RAN_CAEEL (3-205): 3.44e-97: 283: 88.18
+	Sc
		698847 YRB1_YEAST (1290-1471): 3.78e-42: 155: 38.80		GSP1_YEAST (1-214): 5.23e-83: 247: 80.56
+	Sp
		660086 RANG_SCHPO (1280-1470): 6.17e-39: 147: 32.47		SPI1_SCHPO (1-214): 1.23e-84: 251: 80.84
+	At
		785000 RBP1A_ARATH (1015-1240): 1.6e-35: 137: 26.32		RAN2_ARATH (1-215): 1.36e-88: 261: 74.77
+	Sc
		698835 YRB2_YEAST (862-1170): 4.85e-36: 142: 19.03		GSP1_YEAST (1-214): 5.23e-83: 247: 80.56
+	Hs
		919269 RANB3_HUMAN (941-1512): 6.99e-37: 150: 14.02		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	At
		1210455 RBP1A_ARATH (1015-1240): 1.6e-35: 137: 26.32		RAN3_ARATH (1-215): 9.1e-84: 249: 74.31
+	Hs
		834710 RBP2_HUMAN (665-1176): 4.52e-35: 149: 23.71		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		796725 RANG_HUMAN (1309-1507): 3.28e-35: 135: 36.63		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		919306 NUP50_HUMAN (1149-1467): 1.93e-32: 135: 18.01		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		591920 GCC2_HUMAN (1016-1758): 1.57e-56: 219: 23.48		RAB4A_HUMAN (11-169): 1.53e-27: 105: 34.57
+	Hs
		845340 NUP50_HUMAN (1149-1467): 1.93e-32: 135: 18.01		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13