HitPredict

Interactor 1: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Interactor 2: PESC (P53261)
Pescadillo homolog (Nucleolar protein 7) (Ribosomal RNA-processing protein 13)
Gene: NOP7

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	30568249, 36929751, 37968396, 37811893, 21825077, 38113283, 22735702
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 606 Sc			1 605
+	Sc
		860870 HAS1_YEAST (6-467): 1.01e-156: 460: 30.98		PESC_YEAST (1-605): 0: 702: 100.00
+	Hs
		132227 DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61		PESC_HUMAN (4-599): 0: 667: 37.40
+	Sc
		624138 DBP2_YEAST (2-402): 7.47e-126: 383: 25.43		PESC_YEAST (1-605): 0: 702: 100.00
+	Hs
		132048 DDX3X_HUMAN (4-406): 1.31e-116: 363: 24.40		PESC_HUMAN (4-599): 0: 667: 37.40
+	Sc
		699706 DRS1_YEAST (21-392): 3.9e-47: 178: 31.75		PESC_YEAST (1-605): 0: 702: 100.00