HitPredict

Interactor 1: S100P (P25815)
Protein S100-P (Migration-inducing gene 9 protein) (MIG9) (Protein S100-E) (S100 calcium-binding protein P)
Gene: S100P

Interactor 2: NEK1 (Q96PY6)
Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)
Gene: NEK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 1258
+	Hs
		148598 S10AA_HUMAN (2-89): 2.29e-30: 104: 44.32		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		639078 S100P_HUMAN (1-95): 3.03e-36: 119: 100.00		SIK2_HUMAN (4-781): 8.83e-134: 434: 15.15
+	Hs
		661437 S10A2_HUMAN (2-95): 5.21e-32: 109: 40.43		SIK2_HUMAN (4-781): 8.83e-134: 434: 15.15
+	Hs
		682050 CRNN_HUMAN (1-94): 2.31e-32: 118: 35.11		AKT1_HUMAN (1-316): 5.31e-119: 380: 27.41
+	Hs
		707403 S10A3_HUMAN (3-93): 6.58e-30: 103: 32.97		AKT3_HUMAN (1-316): 3.67e-120: 383: 27.03
+	Hs
		681685 S10A3_HUMAN (3-93): 6.58e-30: 103: 32.97		AKT1_HUMAN (1-316): 5.31e-119: 380: 27.41
+	Hs
		682028 S10AE_HUMAN (2-83): 9.09e-21: 80.7: 25.61		AKT1_HUMAN (1-316): 5.31e-119: 380: 27.41
+	Hs
		851575 HORN_HUMAN (1-92): 3.02e-34: 125: 34.78		NEK4_HUMAN (1-266): 1.31e-78: 279: 50.56
+	Hs
		685173 S10AB_HUMAN (2-92): 1.47e-35: 118: 40.66		NEK8_HUMAN (1-255): 2.18e-69: 249: 48.44
+	Hs
		851333 FILA2_HUMAN (1-92): 2.45e-29: 111: 41.30		NEK2_HUMAN (2-259): 6.99e-51: 188: 42.32
+	Hs
		678425 S10A7_HUMAN (2-93): 2.88e-21: 81.8: 26.60		NEK2_HUMAN (2-259): 6.99e-51: 188: 42.32