HitPredict

Interactor 1: CKB11 (P25859)
Cyclin-dependent kinase B1-1 (CDKB1;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog B)
Gene: CDKB1-1

Interactor 2: CCA21 (Q39071)
Cyclin-A2-1 (Cyc3a-At) (Cyclin-3a) (G2/mitotic-specific cyclin-A2-1) (CycA2;1)
Gene: CYCA2-1

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	20407024, 20706207
Identification Methods	protein complementation assay, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 At			1 443
+	At
		1103352 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCA21_ARATH (1-443): 4.19e-152: 440: 100.00
+	At
		1059417 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCA22_ARATH (1-443): 9.64e-131: 386: 64.06
+	At
		639335 CKB11_ARATH (1-309): 3.71e-138: 394: 100.00		CCA22_ARATH (1-443): 9.64e-131: 386: 64.06
+	At
		1103366 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCA24_ARATH (11-441): 7.55e-126: 374: 47.16
+	At
		1103349 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCA23_ARATH (18-441): 8.95e-122: 363: 46.49
+	At
		639339 CKB11_ARATH (1-309): 3.71e-138: 394: 100.00		CCA23_ARATH (18-441): 8.95e-122: 363: 46.49
+	Hs
		625350 CDK2_HUMAN (1-307): 1.5e-139: 397: 53.25		CCNA1_HUMAN (83-439): 5.54e-114: 344: 35.20
+	At
		1103369 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCA31_ARATH (85-442): 4.07e-114: 340: 40.22
+	At
		1103371 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCB23_ARATH (9-437): 4.55e-112: 338: 27.88
+	At
		1103353 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCA34_ARATH (86-442): 4.45e-111: 333: 40.00
+	Hs
		538471 CDK2_HUMAN (1-307): 1.5e-139: 397: 53.25		CCNB1_HUMAN (35-439): 1.11e-110: 334: 28.70
+	Hs
		590125 CDK2_HUMAN (1-307): 1.5e-139: 397: 53.25		CCNA2_HUMAN (11-439): 2.71e-108: 328: 28.37
+	Hs
		303829 CDK2_HUMAN (1-307): 1.5e-139: 397: 53.25		CCNB2_HUMAN (44-436): 1.94e-107: 325: 27.78
+	At
		1103350 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCB12_ARATH (14-439): 1.57e-105: 322: 28.67
+	At
		639340 CKB11_ARATH (1-309): 3.71e-138: 394: 100.00		CCB12_ARATH (14-439): 1.57e-105: 322: 28.67
+	At
		672516 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCB11_ARATH (55-439): 4.08e-95: 294: 28.20
+	At
		1103376 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCB31_ARATH (42-439): 1.66e-94: 292: 27.86
+	At
		639330 CKB11_ARATH (1-309): 3.71e-138: 394: 100.00		CCB11_ARATH (55-439): 4.08e-95: 294: 28.20
+	At
		639341 CKB11_ARATH (1-309): 3.71e-138: 394: 100.00		CCB21_ARATH (16-440): 1.59e-93: 290: 29.95
+	At
		1103351 CKB12_ARATH (1-309): 1.09e-139: 398: 87.78		CCB22_ARATH (16-430): 1.92e-90: 282: 28.13