HitPredict

Interactor 1: UBCD1 (P25867)
Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: eff

Interactor 2: Q9VJB0 (Q9VJB0)
Elfless, isoform B (Elfless, isoform C) (MIP08280p)
Gene: elfless

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Dm			1 229
+	Hs
		1377466 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRAF6_HUMAN (113-226): 4.43e-27: 110: 30.77
+	Hs
		849496 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRAF6_HUMAN (113-226): 4.43e-27: 110: 30.77
+	Zm
		39810 B4FCQ9_MAIZE (1-147): 7.44e-83: 241: 78.23		A0A1D6N2L7_MAIZE (47-218): 1.77e-26: 104: 18.97
+	At
		715137 UBC9_ARATH (1-147): 5.36e-82: 239: 78.91		RNG1L_ARATH (65-228): 2.46e-26: 105: 14.55
+	Hs
		941604 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RNF4_HUMAN (67-229): 6.19e-26: 101: 17.54
+	Hs
		849306 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		RNF4_HUMAN (67-229): 6.19e-26: 101: 17.54
+	Hs
		1205159 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		DZIP3_HUMAN (63-226): 2.34e-22: 97.1: 16.58
+	Dm
		639396 UBCD1_DROME (1-147): 6.04e-82: 239: 100.00		Q8I0J6_DROME (1-229): 1.31e-24: 100: 22.94
+	Dm
		639405 UBCD1_DROME (1-147): 6.04e-82: 239: 100.00		Q9VNJ0_DROME (1-229): 1.91e-24: 100: 22.94
+	Hs
		1299596 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		UHRF2_HUMAN (62-223): 2.6e-22: 96.7: 21.21
+	Hs
		849362 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		DZIP3_HUMAN (63-226): 2.34e-22: 97.1: 16.58
+	Hs
		849415 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		UHRF2_HUMAN (62-223): 2.6e-22: 96.7: 21.21
+	Hs
		1160856 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RFWD3_HUMAN (59-228): 1.38e-20: 91.7: 14.69
+	Hs
		849343 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		RFWD3_HUMAN (59-228): 1.38e-20: 91.7: 14.69
+	Hs
		849377 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		COP1_HUMAN (170-228): 1.42e-17: 83.1: 23.73
+	Hs
		1290204 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RN125_HUMAN (144-218): 5.19e-15: 73.5: 36.71
+	Hs
		849405 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		RN125_HUMAN (144-218): 5.19e-15: 73.5: 36.71
+	Dm
		639398 UBCD1_DROME (1-147): 6.04e-82: 239: 100.00		Q8IR26_DROME (114-228): 4.62e-14: 71.5: 25.62
+	Hs
		1377468 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RN114_HUMAN (165-219): 2.35e-10: 60.3: 36.36
+	Hs
		849499 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		RN114_HUMAN (165-219): 2.35e-10: 60.3: 36.36