HitPredict

Interactor 1: UBCD1 (P25867)
Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: eff

Interactor 2: Q9VJW5 (Q9VJW5)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: DmelCG9014

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0000209 - protein polyubiquitination GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Dm			1 328
+	Mm
		895982 UB2D1_MOUSE (1-147): 1.19e-82: 241: 89.12		RNF41_MOUSE (1-321): 1.67e-83: 256: 43.93
+	Hs
		1318719 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRIM5_HUMAN (5-308): 5.73e-47: 166: 16.72
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI39_HUMAN (9-248): 2.61e-45: 163: 18.22
+	Hs
		1285831 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI43_HUMAN (6-252): 3.58e-45: 161: 16.40
+	Hs
		537142 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI27_HUMAN (3-275): 7.73e-45: 161: 14.58
+	Hs
		1377469 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI17_HUMAN (3-256): 2.65e-44: 159: 14.29
+	Hs
		1354526 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI10_HUMAN (3-279): 8.33e-42: 153: 13.56
+	Hs
		135045 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI38_HUMAN (3-274): 1.23e-39: 146: 16.32
+	Hs
		135012 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRI38_HUMAN (3-274): 1.23e-39: 146: 16.32
+	Hs
		1204911 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI50_HUMAN (3-242): 1.23e-37: 141: 15.98
+	Hs
		1318532 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI31_HUMAN (3-269): 5.13e-38: 141: 13.88
+	Hs
		262201 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRIM3_HUMAN (16-294): 1.72e-36: 141: 13.95
+	Hs
		1356055 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRIM1_HUMAN (2-277): 3.5e-36: 140: 12.95
+	Hs
		1151762 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		Q6GX22_HUMAN (9-277): 2.17e-34: 134: 12.91
+	Hs
		1216737 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		SIAH1_HUMAN (11-137): 8.01e-31: 119: 21.26
+	Hs
		1377466 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRAF6_HUMAN (2-158): 9.82e-29: 117: 26.95
+	Hs
		1252560 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		LNX1_HUMAN (8-107): 1.11e-19: 91.7: 30.69
+	Hs
		1163056 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRAF7_HUMAN (8-132): 2.56e-14: 75.5: 21.43
+	Hs
		1283434 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RN166_HUMAN (9-118): 1.22e-13: 71.3: 24.32
+	Hs
		1261313 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RN138_HUMAN (1-107): 2.08e-11: 64.8: 26.85