HitPredict

Interactor 1: UBCD1 (P25867)
Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: eff

Interactor 2: Q9VXP1 (Q9VXP1)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: sordd1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Dm			1 277
+	Dm
		639398 UBCD1_DROME (1-147): 6.04e-82: 239: 100.00		Q8IR26_DROME (1-276): 7.03e-73: 226: 91.30
+	Hs
		1292368 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RN185_HUMAN (89-277): 2.19e-53: 173: 53.16
+	Hs
		849409 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		RN185_HUMAN (89-277): 2.19e-53: 173: 53.16
+	Hs
		1307272 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		RNF5_HUMAN (103-241): 2.62e-42: 144: 55.40
+	Hs
		849424 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		RNF5_HUMAN (103-241): 2.62e-42: 144: 55.40
+	Hs
		849314 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRI26_HUMAN (120-235): 6.4e-30: 119: 20.80
+	Hs
		849366 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRI22_HUMAN (118-240): 7.26e-30: 119: 17.97
+	Hs
		849406 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRI11_HUMAN (113-235): 5.58e-30: 118: 21.14
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI39_HUMAN (124-235): 4.92e-28: 114: 19.47
+	Hs
		584907 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		RO52_HUMAN (121-233): 2.97e-28: 114: 20.18
+	Hs
		849453 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRI39_HUMAN (124-235): 4.92e-28: 114: 19.47
+	Hs
		537142 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI27_HUMAN (124-256): 1.7e-27: 112: 18.38
+	Hs
		135045 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		TRI38_HUMAN (111-235): 2.98e-27: 111: 16.79
+	Hs
		536760 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRI27_HUMAN (124-256): 1.7e-27: 112: 18.38
+	Hs
		135012 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		TRI38_HUMAN (111-235): 2.98e-27: 111: 16.79
+	Hs
		536779 UB2D2_HUMAN (1-147): 3.06e-82: 239: 94.56		TRI27_HUMAN (124-256): 1.7e-27: 112: 18.38
+	Hs
		135019 UB2D2_HUMAN (1-147): 3.06e-82: 239: 94.56		TRI38_HUMAN (111-235): 2.98e-27: 111: 16.79
+	Hs
		849487 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		CBLC_HUMAN (56-191): 1.01e-25: 107: 22.46
+	At
		715141 UBC9_ARATH (1-147): 5.36e-82: 239: 78.91		Q9LN67_ARATH (123-211): 3.97e-27: 106: 47.87
+	Hs
		749252 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		BRCA1_HUMAN (124-174): 2.67e-16: 80.7: 35.29