HitPredict

Interactor 1: UBCD1 (P25867)
Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: eff

Interactor 2: Q9W418 (Q9W418)
GH17761p (Ubiquitin-5E, isoform A) (Ubiquitin-5E, isoform B)
Gene: Ubi-p5E

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Dm			1 534
+	Xl
		919927 UB2D2_XENLA (1-147): 3.06e-82: 239: 94.56		Q7SY79_XENLA (1-457): 0: 565: 99.78
+	At
		1091932 UBC28_ARATH (1-147): 2.93e-83: 242: 78.91		UBQ3_ARATH (77-381): 3.27e-122: 362: 95.74
+	At
		715116 UBC8_ARATH (1-147): 1.75e-82: 240: 78.91		UBQ3_ARATH (77-381): 3.27e-122: 362: 95.74
+	At
		715157 UBC11_ARATH (1-147): 2.38e-82: 240: 78.91		UBQ3_ARATH (77-381): 3.27e-122: 362: 95.74
+	At
		715132 UBC9_ARATH (1-147): 5.36e-82: 239: 78.91		UBQ3_ARATH (77-381): 3.27e-122: 362: 95.74
+	At
		715147 UBC10_ARATH (1-147): 5.36e-82: 239: 78.23		UBQ3_ARATH (77-381): 3.27e-122: 362: 95.74
+	Hs
		476604 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		475501 UB2D1_HUMAN (1-147): 1.19e-82: 241: 89.12		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		475586 UB2D2_HUMAN (1-147): 3.06e-82: 239: 94.56		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		475550 UB2D3_HUMAN (1-147): 3.31e-81: 237: 93.88		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		476218 UB2E2_HUMAN (4-146): 4.09e-74: 221: 65.73		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		895773 UB2D3_HUMAN (1-147): 3.31e-81: 237: 93.88		RS27A_HUMAN (381-458): 1.34e-41: 148: 97.44
+	Rn
		88580 UB2D1_RAT (1-147): 1.19e-82: 241: 89.12		UBC_RAT (1-108): 3.8e-30: 127: 90.74
+	Hs
		70479 UB2E3_HUMAN (4-146): 1.83e-73: 219: 65.73		B2RDW1_HUMAN (381-458): 1.34e-41: 148: 97.44
+	Mm
		476737 UB2D3_MOUSE (1-147): 3.31e-81: 237: 93.88		UBC_MOUSE (1-108): 3.81e-30: 127: 90.74
+	Hs
		475249 UB2D4_HUMAN (1-147): 2.83e-83: 242: 92.52		UBB_HUMAN (1-77): 5.2e-26: 107: 98.70
+	Hs
		474984 UB2D2_HUMAN (1-147): 3.06e-82: 239: 94.56		UBB_HUMAN (1-77): 5.2e-26: 107: 98.70
+	Sc
		477103 UBC4_YEAST (3-147): 2.49e-79: 232: 80.69		UBI4P_YEAST (1-77): 3.08e-23: 103: 94.81
+	Hs
		171490 UB2D2_HUMAN (1-147): 3.06e-82: 239: 94.56		UBD_HUMAN (231-374): 3.14e-21: 92.4: 31.33
+	Hs
		397879 UB2D3_HUMAN (1-147): 3.31e-81: 237: 93.88		ISG15_HUMAN (307-456): 2.08e-17: 81.6: 32.68