Interactor 1: PREA (P25889)
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA (DPD) (EC 1.3.1.1) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase)
Gene: PREA

Interactor 2: PRET (P76440)
NAD-dependent dihydropyrimidine dehydrogenase subunit PreT (DPD) (EC 1.3.1.1) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase)
Gene: PRET

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.90 0.716

The method score is based on:

Property Details
Experiments 19402753, 16858726
Identification Methods tandem affinity purification, blue native page
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DHO_dh~Fer4_20, DHO_dh~Pyr_redox_2, Fer4_20~Fer4_21
Common GO terms GO:0002058 - uracil binding
GO:0003954 - NADH dehydrogenase activity
GO:0004159 - dihydropyrimidine dehydrogenase (NAD+) activity
GO:0005829 - cytosol
GO:0006208 - pyrimidine nucleobase catabolic process
and 6 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024