HitPredict

Interactor 1: LYN (P25911)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: SRC8 (Q60598)
Src substrate cortactin
Gene: Cttn

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	10428862
Identification Methods	experimental interaction detection
Interaction Type	phosphorylation reaction

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Mm			1 546
+	Hs
		433350 YES_HUMAN (1-510): 0: 585: 53.70		SRC8_HUMAN (1-546): 6.05e-164: 478: 92.18
+	Hs
		522981 SRC_HUMAN (1-510): 0: 579: 51.87		SRC8_HUMAN (1-546): 6.05e-164: 478: 92.18
+	Hs
		789066 ABL2_HUMAN (20-509): 5.9e-165: 499: 36.85		SRC8_HUMAN (1-546): 6.05e-164: 478: 92.18
+	Hs
		433551 LYN_HUMAN (1-512): 0: 612: 96.09		HCLS1_HUMAN (1-546): 7.36e-117: 356: 38.39
+	Mm
		639438 LYN_MOUSE (1-512): 0: 613: 100.00		HCLS1_MOUSE (1-545): 9.09e-116: 353: 41.28
+	Mm
		411921 LCK_MOUSE (1-512): 0: 591: 62.72		HCLS1_MOUSE (1-545): 9.09e-116: 353: 41.28
+	Mm
		763381 FYN_MOUSE (1-510): 0: 580: 53.18		HCLS1_MOUSE (1-545): 9.09e-116: 353: 41.28
+	Hs
		454795 FGR_HUMAN (1-510): 0: 566: 53.42		HCLS1_HUMAN (1-546): 7.36e-117: 356: 38.39
+	Hs
		433732 LYN_HUMAN (1-512): 0: 612: 96.09		MYO1E_HUMAN (175-545): 1.43e-42: 165: 15.23
+	Hs
		433753 LYN_HUMAN (1-512): 0: 612: 96.09		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Mm
		639449 LYN_MOUSE (1-512): 0: 613: 100.00		DBNL_MOUSE (341-546): 3.42e-35: 138: 28.83
+	Hs
		411715 LCK_HUMAN (1-512): 0: 585: 62.33		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Hs
		433354 YES_HUMAN (1-510): 0: 585: 53.70		LASP1_HUMAN (302-545): 2.98e-38: 143: 20.88
+	Hs
		433781 LYN_HUMAN (1-512): 0: 612: 96.09		ITSN1_HUMAN (244-544): 1.82e-18: 91.7: 12.14
+	Hs
		412328 FYN_HUMAN (1-510): 0: 580: 53.37		SH3G2_HUMAN (359-545): 1.14e-28: 118: 21.13
+	Hs
		337470 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Hs
		337296 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		SPTA1_HUMAN (140-545): 1.3e-34: 141: 15.12
+	Hs
		360640 BTK_HUMAN (4-505): 7.92e-164: 481: 33.84		SPTA1_HUMAN (140-545): 1.3e-34: 141: 15.12
+	Hs
		235462 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		VINEX_HUMAN (233-542): 2.72e-15: 80.8: 15.89
+	Hs
		235483 ABL2_HUMAN (20-509): 5.9e-165: 499: 36.85		VINEX_HUMAN (233-542): 2.72e-15: 80.8: 15.89