HitPredict

Interactor 1: LYN (P25911)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: KHDR1 (Q60749)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: Khdrbs1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10844001
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0017124 - SH3 domain binding GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Mm			1 443
+	Hs
		433719 LYN_HUMAN (1-512): 0: 612: 96.09		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Mm
		403437 SRC_MOUSE (1-510): 0: 580: 51.96		KHDR1_MOUSE (1-443): 0: 522: 100.00
+	Mm
		763394 FYN_MOUSE (1-510): 0: 580: 53.18		KHDR1_MOUSE (1-443): 0: 522: 100.00
+	Mm
		980964 YES_MOUSE (1-510): 0: 577: 53.16		KHDR1_MOUSE (1-443): 0: 522: 100.00
+	Hs
		442815 HCK_HUMAN (1-512): 0: 599: 71.48		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		411689 LCK_HUMAN (1-512): 0: 585: 62.33		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		433330 YES_HUMAN (1-510): 0: 585: 53.70		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		412149 FYN_HUMAN (1-510): 0: 580: 53.37		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		522933 SRC_HUMAN (1-510): 0: 579: 51.87		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		454827 FGR_HUMAN (1-510): 0: 566: 53.42		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		789110 FRK_HUMAN (23-506): 0: 527: 47.80		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		991737 ITK_HUMAN (2-503): 1.15e-174: 507: 34.11		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		782780 CSK_HUMAN (64-503): 1.65e-174: 500: 38.19		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		433822 LYN_HUMAN (1-512): 0: 612: 96.09		KHDR2_HUMAN (99-443): 2.28e-131: 384: 61.19
+	Hs
		986367 BTK_HUMAN (4-505): 7.92e-164: 481: 33.84		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Hs
		991758 PTK6_HUMAN (58-506): 6.5e-161: 466: 38.99		KHDR1_HUMAN (1-443): 1.22e-174: 498: 94.36
+	Mm
		763412 FYN_MOUSE (1-510): 0: 580: 53.18		KHDR2_MOUSE (100-443): 2.67e-128: 376: 60.23
+	Dm
		337713 SRC64_DROME (25-510): 6.39e-180: 518: 43.95		Q9W255_DROME (62-398): 2.68e-79: 252: 34.13
+	Hs
		337484 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		SF01_HUMAN (81-288): 6.17e-55: 195: 22.07
+	Hs
		789069 ABL2_HUMAN (20-509): 5.9e-165: 499: 36.85		SF01_HUMAN (81-288): 6.17e-55: 195: 22.07