HitPredict

Interactor 1: LYN (P25911)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: DBNL (Q62418)
Drebrin-like protein (Actin-binding protein 1) (SH3 domain-containing protein 7)
Gene: DBNL

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	10428862
Identification Methods	experimental interaction detection
Interaction Type	phosphorylation reaction

Property	Details
Interacting Pfam domains	Cofilin_ADF~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0002250 - adaptive immune response GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Mm			1 436
+	Hs
		433372 YES_HUMAN (1-510): 0: 585: 53.70		DREB_HUMAN (2-384): 8.55e-64: 218: 29.10
+	Mm
		639446 LYN_MOUSE (1-512): 0: 613: 100.00		SRC8_MOUSE (121-436): 6.4e-37: 143: 27.04
+	Hs
		433551 LYN_HUMAN (1-512): 0: 612: 96.09		HCLS1_HUMAN (122-436): 2.4e-34: 135: 24.14
+	Mm
		639438 LYN_MOUSE (1-512): 0: 613: 100.00		HCLS1_MOUSE (122-435): 2.81e-32: 129: 23.59
+	Hs
		411580 LCK_HUMAN (1-512): 0: 585: 62.33		VAV_HUMAN (87-434): 4.09e-39: 152: 15.94
+	Hs
		411981 FYN_HUMAN (1-510): 0: 580: 53.37		VAV_HUMAN (87-434): 4.09e-39: 152: 15.94
+	Hs
		433350 YES_HUMAN (1-510): 0: 585: 53.70		SRC8_HUMAN (121-436): 1.14e-37: 145: 25.79
+	Hs
		522981 SRC_HUMAN (1-510): 0: 579: 51.87		SRC8_HUMAN (121-436): 1.14e-37: 145: 25.79
+	Mm
		411921 LCK_MOUSE (1-512): 0: 591: 62.72		HCLS1_MOUSE (122-435): 2.81e-32: 129: 23.59
+	Mm
		763381 FYN_MOUSE (1-510): 0: 580: 53.18		HCLS1_MOUSE (122-435): 2.81e-32: 129: 23.59
+	Hs
		454795 FGR_HUMAN (1-510): 0: 566: 53.42		HCLS1_HUMAN (122-436): 2.4e-34: 135: 24.14
+	Hs
		433781 LYN_HUMAN (1-512): 0: 612: 96.09		ITSN1_HUMAN (265-435): 1.16e-09: 62.8: 14.86
+	Hs
		433354 YES_HUMAN (1-510): 0: 585: 53.70		LASP1_HUMAN (224-435): 1.31e-15: 78.5: 24.89
+	Hs
		337333 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		VAV_HUMAN (87-434): 4.09e-39: 152: 15.94
+	Hs
		207757 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		PPIP1_HUMAN (103-435): 6.08e-38: 144: 15.68
+	Mm
		337624 ABL1_MOUSE (31-509): 8.09e-168: 505: 38.01		PPIP1_MOUSE (104-435): 1.12e-37: 143: 16.37
+	Hs
		412328 FYN_HUMAN (1-510): 0: 580: 53.37		SH3G2_HUMAN (333-435): 1.96e-11: 66.9: 32.04
+	Hs
		789066 ABL2_HUMAN (20-509): 5.9e-165: 499: 36.85		SRC8_HUMAN (121-436): 1.14e-37: 145: 25.79
+	Hs
		337550 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		PACN1_HUMAN (61-435): 2.19e-32: 129: 17.28
+	Hs
		337572 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		ABI2_HUMAN (225-435): 1.74e-11: 68.1: 19.49