Interactor 1: LYN (P25911)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN
Interactor 2: PLCG2 (Q8CIH5)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-gamma-2) (PLC-gamma-2)
Gene: PLCG2
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8395016 |
| Identification Methods | anti bait coimmunoprecipitation, pull down |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, C2~SH2, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031663 - lipopolysaccharide-mediated signaling pathway GO:0035556 - intracellular signal transduction GO:0043410 - positive regulation of MAPK cascade and 6 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
