HitPredict

Interactor 1: LYN (P25911)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: ANR54 (Q91WK7)
Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein)
Gene: Ankrd54

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0044877 - protein-containing complex binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 512 Mm			1 299
+	Hs
		433832 LYN_HUMAN (1-512): 0: 612: 96.09		ANR54_HUMAN (1-299): 1.34e-88: 267: 90.67
+	Hs
		433389 YES_HUMAN (1-510): 0: 585: 53.70		ANR54_HUMAN (1-299): 1.34e-88: 267: 90.67
+	Hs
		523028 SRC_HUMAN (1-510): 0: 579: 51.87		ANR54_HUMAN (1-299): 1.34e-88: 267: 90.67
+	Hs
		846484 BLK_HUMAN (1-512): 0: 547: 60.23		ANR54_HUMAN (1-299): 1.34e-88: 267: 90.67
+	Hs
		433701 LYN_HUMAN (1-512): 0: 612: 96.09		ANK2_HUMAN (76-296): 3.13e-56: 197: 21.94
+	Hs
		434071 LYN_HUMAN (1-512): 0: 612: 96.09		KDIS_HUMAN (3-225): 2.69e-56: 197: 18.80
+	Hs
		433730 LYN_HUMAN (1-512): 0: 612: 96.09		ANK3_HUMAN (1-194): 5.74e-53: 188: 17.82
+	Hs
		411885 LCK_HUMAN (1-512): 0: 585: 62.33		KDIS_HUMAN (3-225): 2.69e-56: 197: 18.80
+	Hs
		411697 LCK_HUMAN (1-512): 0: 585: 62.33		ANK3_HUMAN (1-194): 5.74e-53: 188: 17.82
+	Hs
		788998 TEC_HUMAN (2-506): 9.8e-170: 495: 33.33		ANR54_HUMAN (1-299): 1.34e-88: 267: 90.67
+	Hs
		986383 BTK_HUMAN (4-505): 7.92e-164: 481: 33.84		ANR54_HUMAN (1-299): 1.34e-88: 267: 90.67
+	Mm
		976833 ITK_MOUSE (2-503): 8.23e-175: 507: 35.55		ANR54_MOUSE (1-299): 2.4e-71: 223: 100.00
+	Dm
		337696 SRC64_DROME (25-510): 6.39e-180: 518: 43.95		TNKS_DROME (2-295): 6.09e-52: 184: 16.11
+	Hs
		337406 ABL1_HUMAN (31-509): 9.89e-168: 505: 38.01		DAPK1_HUMAN (72-297): 1.95e-49: 178: 16.59
+	Hs
		434072 LYN_HUMAN (1-512): 0: 612: 96.09		ANR50_HUMAN (189-297): 8.27e-09: 58.6: 11.93