Interactor 1: BMI1 (P25916)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)
Gene: BMI1
Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35390228, 9627119, 23207902, 17296600, 16710298, 12183370, 18650381, 16359901 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, x-ray crystallography, molecular sieving, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RAWUL~RAWUL, zf-C3HC4_2~zf-C3HC4_2 |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000151 - ubiquitin ligase complex GO:0000792 - heterochromatin GO:0003682 - chromatin binding GO:0005634 - nucleus and 6 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
